I think I lost a 3TB drive on my Windows Home Server 2011 box today. All the client PC backups were on that drive but no data that I recall so it's not a great loss.
Of course I have not automated a backup of the servers pictures, videos, and documents. I do have a Microsoft Richcopy script to do so manually to another 3TB drive on that server. I miss the Drive Extender technology in the old Windows Home Server to manage a copy of the data that would survive a one hard disk crash.
My last ditch backup is on such a Windows Home Server V1 box. I haven't had that running in awhile so there are 23 patches to apply before looking to make a copy there.
Maybe my life will slow down enough so I can get all the solutions automated and bulletproof. Or Microsoft could make an alternative to do it for me (Apple - hah! They abandoned the server space). There are some interesting articles on using Windows 8 and the Storage Spaces capability acting as a home server but I'd like something more tried & true.